Subsegmental transcatheter arterial embolization for small hepatocellular carcinomas : local therapeutic effect and 5-year survival rate

The local therapeutic effects and 5-year survival rates obtained following subsegmental transcatheter arterial embolization (TAE) therapy for small hepatocellular carcinomas (HCCs) were retrospectively analyzed. A total of 124 nodular-type HCC lesions measuring less than 4 cm in diameter in 100 pati...

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Veröffentlicht in:Cancer chemotherapy and pharmacology 1994-01, Vol.33 (S1), p.S84-S88
Hauptverfasser: MATSUI, O, KADOYA, M, YSOHIKAWA, J, GABATA, T, TAKASHIMA, T, DEMACHI, H
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Sprache:eng
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Zusammenfassung:The local therapeutic effects and 5-year survival rates obtained following subsegmental transcatheter arterial embolization (TAE) therapy for small hepatocellular carcinomas (HCCs) were retrospectively analyzed. A total of 124 nodular-type HCC lesions measuring less than 4 cm in diameter in 100 patients with liver cirrhosis were subjected to the analysis. All lesions became opaque on digital subtraction angiography. Complete necrosis was seen in 64% of 11 resected lesions. Among the remaining 113 lesions, the 1- and 5-year local recurrence rates following one performance of TAE were 18% and 33%, respectively. The 1- and 5-year survival rates were 100% and 53%, respectively. No significant side effect was observed after TAE therapy. Subsegmental TAE therapy significantly improved the long-term survival rates of patients with small HCCs associated with liver cirrhosis as compared with those treated by conventional TAE therapy.
ISSN:0344-5704
1432-0843
DOI:10.1007/bf00686674