Characteristics of Four New Human Cell Lines Derived From Squamous Cell Carcinomas of the Head and Neck

Four human cell lines were established from biopsy specimens of squamous cell carcinomas of the larynx (TR131 and TR138), tongue (TR126), and buccal mucosa that had infiltrated a lymph node (TR146). All 4 lines readily formed colonies on a plastic substratum, but they were virtually incapable of for...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1985-10, Vol.75 (4), p.621-635
Hauptverfasser:	Rupniak, H. Thomas, Rowlatt, Charles, Lane, E. Birgitte, Steele, John G., Trejdosiewicz, Ludwik K., Laskiewicz, Bozena, Povey, Susan, Hill, Bridget T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Biological and medical sciences Carcinoma, Squamous Cell - analysis Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - ultrastructure Cell Differentiation Cell Line Cytoskeleton - analysis Female Head and Neck Neoplasms - analysis Head and Neck Neoplasms - pathology Head and Neck Neoplasms - ultrastructure Humans Keratins - analysis Lectins - metabolism Male Medical sciences Mice Mice, Nude Middle Aged Neoplasm Transplantation Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Transplantation, Heterologous
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Zusammenfassung:	Four human cell lines were established from biopsy specimens of squamous cell carcinomas of the larynx (TR131 and TR138), tongue (TR126), and buccal mucosa that had infiltrated a lymph node (TR146). All 4 lines readily formed colonies on a plastic substratum, but they were virtually incapable of forming colonies in an anchorage-independent semisolid support system of soft agar (cloning efficiencies,
ISSN:	0027-8874 1460-2105
DOI:	10.1093/jnci/75.4.621