The Top Ten NSAIDs: A molecular modelling study
In the present study the Top Ten NSAIDs are investigated with the aid of molecular modelling methods. Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds.
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| Veröffentlicht in: | Pharmaceutica acta Helvetiae 1994-01, Vol.68 (3), p.181-189 |
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| container_end_page | 189 |
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| container_title | Pharmaceutica acta Helvetiae |
| container_volume | 68 |
| creator | Winiwarter, S. Roth, H.J. |
| description | In the present study the Top Ten NSAIDs are investigated with the aid of molecular modelling methods. Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds. |
| doi_str_mv | 10.1016/0031-6865(94)90041-8 |
| format | Article |
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Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds.</description><identifier>ISSN: 0031-6865</identifier><identifier>DOI: 10.1016/0031-6865(94)90041-8</identifier><identifier>PMID: 8121927</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Anti-Inflammatory Agents, Non-Steroidal - chemistry ; Anti-Inflammatory Agents, Non-Steroidal - pharmacology ; Biological and medical sciences ; Bones, joints and connective tissue. Antiinflammatory agents ; Conformational analysis ; Medical sciences ; Models, Molecular ; Molecular modelling ; NSAID ; Pharmacology. 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Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds.</description><subject>Anti-Inflammatory Agents, Non-Steroidal - chemistry</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Bones, joints and connective tissue. Antiinflammatory agents</subject><subject>Conformational analysis</subject><subject>Medical sciences</subject><subject>Models, Molecular</subject><subject>Molecular modelling</subject><subject>NSAID</subject><subject>Pharmacology. 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Antiinflammatory agents</topic><topic>Conformational analysis</topic><topic>Medical sciences</topic><topic>Models, Molecular</topic><topic>Molecular modelling</topic><topic>NSAID</topic><topic>Pharmacology. Drug treatments</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Winiwarter, S.</creatorcontrib><creatorcontrib>Roth, H.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmaceutica acta Helvetiae</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Winiwarter, S.</au><au>Roth, H.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Top Ten NSAIDs: A molecular modelling study</atitle><jtitle>Pharmaceutica acta Helvetiae</jtitle><addtitle>Pharm Acta Helv</addtitle><date>1994-01</date><risdate>1994</risdate><volume>68</volume><issue>3</issue><spage>181</spage><epage>189</epage><pages>181-189</pages><issn>0031-6865</issn><abstract>In the present study the Top Ten NSAIDs are investigated with the aid of molecular modelling methods. 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| fulltext | fulltext |
| identifier | ISSN: 0031-6865 |
| ispartof | Pharmaceutica acta Helvetiae, 1994-01, Vol.68 (3), p.181-189 |
| issn | 0031-6865 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76385616 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Conformational analysis Medical sciences Models, Molecular Molecular modelling NSAID Pharmacology. Drug treatments Structure-Activity Relationship |
| title | The Top Ten NSAIDs: A molecular modelling study |
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