The Top Ten NSAIDs: A molecular modelling study

In the present study the Top Ten NSAIDs are investigated with the aid of molecular modelling methods. Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds.

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Bibliographische Detailangaben
Veröffentlicht in:	Pharmaceutica acta Helvetiae 1994-01, Vol.68 (3), p.181-189
Hauptverfasser:	Winiwarter, S., Roth, H.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Conformational analysis Medical sciences Models, Molecular Molecular modelling NSAID Pharmacology. Drug treatments Structure-Activity Relationship
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Beschreibung
Zusammenfassung:	In the present study the Top Ten NSAIDs are investigated with the aid of molecular modelling methods. Conformational analyses are performed, electronic and lipophilic properties are examined and correlated with the antiinflammatory effectivity of the respective compounds.
ISSN:	0031-6865
DOI:	10.1016/0031-6865(94)90041-8