A sialic acid-binding lectin from the mushroom Hericium erinaceum

A lectin was isolated from the mushroom Hericium erinaceum. This lectin is composed of two different subunits of 15 and 16 kDa and the molecular mass of the intact lectin was estimated to be 54 kDa by gel filtration. It exhibits specificity towards sialic acids, especially N-glycolylneuraminic acid.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 1994-02, Vol.340 (1), p.56-58
Hauptverfasser:	Kawagishi, Hirokazu, Mori, Hironobu, Uno, Akinori, Kimura, Atsuo, Chiba, Seiya
Format:	Artikel
Sprache:	eng
Schlagworte:	all sugars are of d-configuration, unless otherwise stated Amino Acids - analysis Analytical, structural and metabolic biochemistry Basidiomycota - chemistry Binding and carrier proteins Biological and medical sciences BSM, bovine submaxillary mucin Chromatography, Gel Chromatography, Ion Exchange Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - isolation & purification Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Fungus HEL, Hericium erinaceum lectin Hericium erinaceum Lectin Lectins - chemistry Lectins - isolation & purification Mushroom NeuAc, N-acetylneuraminic acid NeuGc, N-glycolylneuraminic acid PBS, 10 mM phosphated-buffered saline (pH 7.4), SDS-PAGE, sodium dodecylsulfate-polyacrylamide gel electrophoresis Proteins Purification Sialic Acid Binding Immunoglobulin-like Lectins sialic acid-binding
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A lectin was isolated from the mushroom Hericium erinaceum. This lectin is composed of two different subunits of 15 and 16 kDa and the molecular mass of the intact lectin was estimated to be 54 kDa by gel filtration. It exhibits specificity towards sialic acids, especially N-glycolylneuraminic acid.
ISSN:	0014-5793 1873-3468
DOI:	10.1016/0014-5793(94)80172-X