Identification of viridans streptococci associated with bacteraemia in neutropenic cancer patients

Oral Microbiology, Royal College Surgeons Department of Dental Sciences, King's College School of Medicine and Dentistry, Faculty of Clinical Dentistry, Caldecot Road, London SE5 9RW * Department of Microbiology, Withington Hospital, West Didsbury. Manchester M20 8LR Received August 24, 1993 Accepted August 31, 1993 SUMMARY: Twenty-three viridans streptococcal isolates from pyrexial neutropenic patients with various malignant diseases were studied in a comprehensive identification scheme. Fourteen isolates were identified as Streptococcus oralis , five as S. mitis and two as S. salivarius but the remaining two could not be identified reliably. The virulence mechanisms associated with the ability of these species to survive and grow in vivo require further investigation but may involve the production of specific glycosidase and proteolytic enzyme activities.