The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment
We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a...
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| Veröffentlicht in: | Scandinavian journal of gastroenterology 1985-01, Vol.20 (6), p.691-695 |
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| container_title | Scandinavian journal of gastroenterology |
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| creator | Naesdal, J. Lind, T. Bergsåker-aspöy, J. Bernklev, T. Farup, P. G. Gillberg, R. Halvorsen, L. Kilander, A. Offergaard, S. Walan, A. Lloyd-Davies, K. A. |
| description | We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a cumulative total of 93%). All patients (100%) had healed by the end of the treatment period. There was no significant difference in healing rate between the two treatment groups. Ulcer symptoms were relieved rapidly, and the drug was well tolerated. |
| doi_str_mv | 10.3109/00365528509089196 |
| format | Article |
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G. ; Gillberg, R. ; Halvorsen, L. ; Kilander, A. ; Offergaard, S. ; Walan, A. ; Lloyd-Davies, K. A.</creator><creatorcontrib>Naesdal, J. ; Lind, T. ; Bergsåker-aspöy, J. ; Bernklev, T. ; Farup, P. G. ; Gillberg, R. ; Halvorsen, L. ; Kilander, A. ; Offergaard, S. ; Walan, A. ; Lloyd-Davies, K. A.</creatorcontrib><description>We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a cumulative total of 93%). All patients (100%) had healed by the end of the treatment period. There was no significant difference in healing rate between the two treatment groups. Ulcer symptoms were relieved rapidly, and the drug was well tolerated.</description><identifier>ISSN: 0036-5521</identifier><identifier>EISSN: 1502-7708</identifier><identifier>DOI: 10.3109/00365528509089196</identifier><identifier>PMID: 3898347</identifier><identifier>CODEN: SJGRA4</identifier><language>eng</language><publisher>Copenhagen: Informa UK Ltd</publisher><subject>Adult ; Aged ; Anti-Ulcer Agents - therapeutic use ; ATPase inhibitor ; Benzimidazole ; Benzimidazoles - administration & dosage ; Benzimidazoles - therapeutic use ; Biological and medical sciences ; clinical trial ; Clinical Trials as Topic ; Digestive system ; duodenal ulcer ; Duodenal Ulcer - drug therapy ; Female ; Gastric Acid - metabolism ; gastric acid secretion ; healing ; Humans ; inhibition ; Male ; Medical sciences ; Middle Aged ; Omeprazole ; peptic ulcer ; Pharmacology. Drug treatments ; substituted ; Time Factors</subject><ispartof>Scandinavian journal of gastroenterology, 1985-01, Vol.20 (6), p.691-695</ispartof><rights>1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-71ff23de8e7558ba63c58a89da1cd1a41518b98a3f7038bb6e97935ebe8f953f3</citedby><cites>FETCH-LOGICAL-c430t-71ff23de8e7558ba63c58a89da1cd1a41518b98a3f7038bb6e97935ebe8f953f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/00365528509089196$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/00365528509089196$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8561649$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3898347$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Naesdal, J.</creatorcontrib><creatorcontrib>Lind, T.</creatorcontrib><creatorcontrib>Bergsåker-aspöy, J.</creatorcontrib><creatorcontrib>Bernklev, T.</creatorcontrib><creatorcontrib>Farup, P. G.</creatorcontrib><creatorcontrib>Gillberg, R.</creatorcontrib><creatorcontrib>Halvorsen, L.</creatorcontrib><creatorcontrib>Kilander, A.</creatorcontrib><creatorcontrib>Offergaard, S.</creatorcontrib><creatorcontrib>Walan, A.</creatorcontrib><creatorcontrib>Lloyd-Davies, K. A.</creatorcontrib><title>The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment</title><title>Scandinavian journal of gastroenterology</title><addtitle>Scand J Gastroenterol</addtitle><description>We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a cumulative total of 93%). All patients (100%) had healed by the end of the treatment period. There was no significant difference in healing rate between the two treatment groups. Ulcer symptoms were relieved rapidly, and the drug was well tolerated.</description><subject>Adult</subject><subject>Aged</subject><subject>Anti-Ulcer Agents - therapeutic use</subject><subject>ATPase inhibitor</subject><subject>Benzimidazole</subject><subject>Benzimidazoles - administration & dosage</subject><subject>Benzimidazoles - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>clinical trial</subject><subject>Clinical Trials as Topic</subject><subject>Digestive system</subject><subject>duodenal ulcer</subject><subject>Duodenal Ulcer - drug therapy</subject><subject>Female</subject><subject>Gastric Acid - metabolism</subject><subject>gastric acid secretion</subject><subject>healing</subject><subject>Humans</subject><subject>inhibition</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Omeprazole</subject><subject>peptic ulcer</subject><subject>Pharmacology. Drug treatments</subject><subject>substituted</subject><subject>Time Factors</subject><issn>0036-5521</issn><issn>1502-7708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1LxDAQhoMoun78AA9CD-KtmmyaJkEvfisIgqznMk0nbiVt1qRF9NfbsqsggqcJvM87M3mHkH1Gjzmj-oRSngsxVYJqqjTT-RqZMEGnqZRUrZPJqKcDwLbIdoyvlFIhM71JNrnSimdyQi5mc0yeoMPE2-QOwdXty_i86n2FLbjk2RkMMan6MCqPDS4CfHqHySwgdA223S7ZsOAi7q3qDnm-uZ5d3qUPj7f3l-cPqck47VLJrJ3yChVKIVQJOTdCgdIVMFMxyJhgqtQKuJWUq7LMUUvNBZaorBbc8h1ytOy7CP6tx9gVTR0NOgct-j4WMudC5lM9gGwJmuBjDGiLRagbCB8Fo8WYW_Ent8FzsGrelw1WP45VUIN-uNIhGnA2QGvq-IMpkbM8G0efLbG6tT408O6Dq4oOPpwP3x7-3xanv-zz4SDd3EDA4tX3YbhH_OcPX8BimVI</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Naesdal, J.</creator><creator>Lind, T.</creator><creator>Bergsåker-aspöy, J.</creator><creator>Bernklev, T.</creator><creator>Farup, P. G.</creator><creator>Gillberg, R.</creator><creator>Halvorsen, L.</creator><creator>Kilander, A.</creator><creator>Offergaard, S.</creator><creator>Walan, A.</creator><creator>Lloyd-Davies, K. A.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Scandinavian University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19850101</creationdate><title>The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment</title><author>Naesdal, J. ; Lind, T. ; Bergsåker-aspöy, J. ; Bernklev, T. ; Farup, P. G. ; Gillberg, R. ; Halvorsen, L. ; Kilander, A. ; Offergaard, S. ; Walan, A. ; Lloyd-Davies, K. 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A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment</atitle><jtitle>Scandinavian journal of gastroenterology</jtitle><addtitle>Scand J Gastroenterol</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>20</volume><issue>6</issue><spage>691</spage><epage>695</epage><pages>691-695</pages><issn>0036-5521</issn><eissn>1502-7708</eissn><coden>SJGRA4</coden><abstract>We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a cumulative total of 93%). All patients (100%) had healed by the end of the treatment period. There was no significant difference in healing rate between the two treatment groups. Ulcer symptoms were relieved rapidly, and the drug was well tolerated.</abstract><cop>Copenhagen</cop><cop>Oslo</cop><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>3898347</pmid><doi>10.3109/00365528509089196</doi><tpages>5</tpages></addata></record> |
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| ispartof | Scandinavian journal of gastroenterology, 1985-01, Vol.20 (6), p.691-695 |
| issn | 0036-5521 1502-7708 |
| language | eng |
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| source | Taylor & Francis:Master (3349 titles); MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Adult Aged Anti-Ulcer Agents - therapeutic use ATPase inhibitor Benzimidazole Benzimidazoles - administration & dosage Benzimidazoles - therapeutic use Biological and medical sciences clinical trial Clinical Trials as Topic Digestive system duodenal ulcer Duodenal Ulcer - drug therapy Female Gastric Acid - metabolism gastric acid secretion healing Humans inhibition Male Medical sciences Middle Aged Omeprazole peptic ulcer Pharmacology. Drug treatments substituted Time Factors |
| title | The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment |
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