The Effect of Hypofibrinogenemia and Fibrinolysis on Skeletal Muscle Function after Ischemia and Reperfusion

The Effect of Hypofibrinogenemia and Fibrinolysis on Skeletal Muscle Function after Ischemia and Reperfusion

Isometric contraction to direct supramaximal tetanic stimulation of the anterior tibialis (AT) muscle was measured in 50 New Zealand White rabbits after ischemia and reperfusion. Ischemia was produced unilaterally by collateral ligation and temporary inflow control until AT muscle function decreased...

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Veröffentlicht in:The Journal of surgical research 1994, Vol.56 (1), p.77-81
Hauptverfasser: Colburn, Michael D., Gelabert, Hugh A., Nowara, Hani, Hajjar, George E., Moore, Wesley S., Quiñones-Baldrich, William J.
Format: Artikel
Sprache:eng
Schlagworte:
Afibrinogenemia - physiopathology
Ancrod - pharmacology
Animals
Biological and medical sciences
Fibrinogen - metabolism
Fibrinolysis
Ischemia - physiopathology
Isometric Contraction
Male
Medical sciences
Muscles - blood supply
Muscles - drug effects
Muscles - physiopathology
Orthopedic surgery
Plasminogen - pharmacology
Rabbits
Reperfusion
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Time Factors
Urokinase-Type Plasminogen Activator - pharmacology
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Zusammenfassung:Isometric contraction to direct supramaximal tetanic stimulation of the anterior tibialis (AT) muscle was measured in 50 New Zealand White rabbits after ischemia and reperfusion. Ischemia was produced unilaterally by collateral ligation and temporary inflow control until AT muscle function decreased to
ISSN:0022-4804
1095-8673
DOI:10.1006/jsre.1994.1013