Unexpected High Incidence of Tumours in Thymectomized Mice treated with Anti-lymphocytic Globulin and Mycobacterium leprae
During an attempt to transmit human leprosy ( Mycobacterium leprae ) to mice, polyoma-type tumours arose in all mice thymectomized as adults and treated with anti-lymphocytic globulin (ALS I g G).
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| Veröffentlicht in: | Nature (London) 1969-03, Vol.221 (5185), p.1033-1036 |
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| container_issue | 5185 |
| container_start_page | 1033 |
| container_title | Nature (London) |
| container_volume | 221 |
| creator | GAUGAS, J. M HARVEY, JENNIFER J CHESTERMAN, F. C HIRSCH, M. S GILCHRIST, C REES, R. J. W |
| description | During an attempt to transmit human leprosy (
Mycobacterium leprae
) to mice, polyoma-type tumours arose in all mice thymectomized as adults and treated with anti-lymphocytic globulin (ALS I
g
G). |
| doi_str_mv | 10.1038/2211033a0 |
| format | Article |
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Mycobacterium leprae
) to mice, polyoma-type tumours arose in all mice thymectomized as adults and treated with anti-lymphocytic globulin (ALS I
g
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Mycobacterium leprae
) to mice, polyoma-type tumours arose in all mice thymectomized as adults and treated with anti-lymphocytic globulin (ALS I
g
G).</description><subject>Adenoma, Pleomorphic</subject><subject>Animals</subject><subject>Antilymphocyte Serum - therapeutic use</subject><subject>Bone Neoplasms</subject><subject>Female</subject><subject>Fibrosarcoma</subject><subject>Humanities and Social Sciences</subject><subject>Immunization, Passive</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Leiomyosarcoma</subject><subject>Leprosy</subject><subject>Lymphocytes - immunology</subject><subject>Mammary Neoplasms, Experimental - pathology</subject><subject>Mice</subject><subject>multidisciplinary</subject><subject>Mycobacterium leprae - pathogenicity</subject><subject>Neoplasms, Experimental - etiology</subject><subject>Neoplasms, Experimental - pathology</subject><subject>Neutralization Tests</subject><subject>Osteosarcoma</subject><subject>Sarcoma</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Thymectomy</subject><subject>Uterine Neoplasms</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtLxDAUhYMoOj4W_gAxK0GhmjZJ0y5FfAyMuBnXJUlvnUib1KRF6683MsO4cXUX5zvncg5Cpym5TgktbrIsjZdKsoNmKRN5wvJC7KIZIVmRkILmB-gwhHdCCE8F20f7jBLGCjZD368WvnrQA9T4ybyt8NxqU4PVgF2Dl2PnRh-wsXi5mrqIuc58R_TZRGDwIH99n2ZY4Vs7mKSdun7l9DQYjR9bp8Y2OqWN_KSdkvGLN2OHW-i9hGO018g2wMnmHqHlw_3y7ilZvDzO724Xiaa0HBIhilqVZZZyyZgqgZVKUEl5wzMpa8KbjAGPfSGXjWRClYrygmdM1HVKQdEjdLGO7b37GCEMVWeChraVFtwYKpHTjHCaR_ByDWrvQvDQVL03nfRTlZLqd-ZqO3Nkzzaho-qg3pKbXaN-tdZDVOwb-Oo9DmljzX_DztewlcPoYRv2R_wARxqQnQ</recordid><startdate>19690315</startdate><enddate>19690315</enddate><creator>GAUGAS, J. 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g
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| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1969-03, Vol.221 (5185), p.1033-1036 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; Nature; SpringerNature Journals |
| subjects | Adenoma, Pleomorphic Animals Antilymphocyte Serum - therapeutic use Bone Neoplasms Female Fibrosarcoma Humanities and Social Sciences Immunization, Passive Immunosuppressive Agents - therapeutic use Leiomyosarcoma Leprosy Lymphocytes - immunology Mammary Neoplasms, Experimental - pathology Mice multidisciplinary Mycobacterium leprae - pathogenicity Neoplasms, Experimental - etiology Neoplasms, Experimental - pathology Neutralization Tests Osteosarcoma Sarcoma Science Science (multidisciplinary) Thymectomy Uterine Neoplasms |
| title | Unexpected High Incidence of Tumours in Thymectomized Mice treated with Anti-lymphocytic Globulin and Mycobacterium leprae |
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