Ciliary Trafficking: CEP290 Guards a Gated Community

A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.

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Veröffentlicht in:Current biology 2010-11, Vol.20 (21), p.R928-R931
Hauptverfasser: Betleja, Ewelina, Cole, Douglas G.
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description A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.
doi_str_mv 10.1016/j.cub.2010.09.058
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subjects Chlamydomonas - genetics
Chlamydomonas - metabolism
Chlamydomonas - ultrastructure
Cilia - metabolism
Cilia - ultrastructure
Membrane Proteins - genetics
Membrane Proteins - metabolism
Membrane Proteins - physiology
Plant Proteins - genetics
Plant Proteins - metabolism
Plant Proteins - physiology
Protein Transport - genetics
title Ciliary Trafficking: CEP290 Guards a Gated Community
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