Direct Pathway to the Brain

Direct Pathway to the Brain

Whole-body autoradiographic studies demonstrated that, when isotopically labeled glucose is placed in the ligated oropharynx, there is a rapid movement of the isotope directly to the intracranial cavity. This passage involves nonspecific diffusion, bypassing all recognized routes to the brain.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1969-02, Vol.163 (3870), p.952-953
Hauptverfasser: Kare, Morley R., Schechter, Paul J., Grossman, Sebastian P., Roth, Lloyd J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Autoradiography
Blood
Brain
Brain Chemistry
Carbon Isotopes
Diffusion
Duodenum
Glucose - administration & dosage
Glucose - metabolism
Isotopes
Isotopic labeling
Male
Mouth
Oropharynx
Perfusion
Radioactive decay
Rats
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Beschreibung
Zusammenfassung:Whole-body autoradiographic studies demonstrated that, when isotopically labeled glucose is placed in the ligated oropharynx, there is a rapid movement of the isotope directly to the intracranial cavity. This passage involves nonspecific diffusion, bypassing all recognized routes to the brain.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.163.3870.952