Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists
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| Veröffentlicht in: | Journal of medicinal chemistry 1985-09, Vol.28 (9), p.1145-1147 |
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| container_end_page | 1147 |
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| container_issue | 9 |
| container_start_page | 1145 |
| container_title | Journal of medicinal chemistry |
| container_volume | 28 |
| creator | Perchonock, Carl D McCarthy, Mary E Erhard, Karl F Gleason, John G Wasserman, Martin A Muccitelli, Roseanna M DeVan, Jeris F Tucker, Stephanie S Vickery, Lynne M |
| description | |
| doi_str_mv | 10.1021/jm00147a004 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-2623 |
| ispartof | Journal of medicinal chemistry, 1985-09, Vol.28 (9), p.1145-1147 |
| issn | 0022-2623 1520-4804 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76284056 |
| source | ACS Publications; MEDLINE |
| subjects | Airway Resistance - drug effects Animals Chemical Phenomena Chemistry Chromones - pharmacology Dicarboxylic Acids - chemical synthesis Dicarboxylic Acids - pharmacology Dose-Response Relationship, Drug Exact sciences and technology Guinea Pigs Lung Compliance - drug effects Muscle Contraction - drug effects Noncondensed benzenic compounds Organic chemistry Preparations and properties Receptors, Leukotriene Receptors, Prostaglandin - drug effects SRS-A - antagonists & inhibitors Trachea - physiology |
| title | Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists |
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