Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists

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Veröffentlicht in:	Journal of medicinal chemistry 1985-09, Vol.28 (9), p.1145-1147
Hauptverfasser:	Perchonock, Carl D, McCarthy, Mary E, Erhard, Karl F, Gleason, John G, Wasserman, Martin A, Muccitelli, Roseanna M, DeVan, Jeris F, Tucker, Stephanie S, Vickery, Lynne M
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Resistance - drug effects Animals Chemical Phenomena Chemistry Chromones - pharmacology Dicarboxylic Acids - chemical synthesis Dicarboxylic Acids - pharmacology Dose-Response Relationship, Drug Exact sciences and technology Guinea Pigs Lung Compliance - drug effects Muscle Contraction - drug effects Noncondensed benzenic compounds Organic chemistry Preparations and properties Receptors, Leukotriene Receptors, Prostaglandin - drug effects SRS-A - antagonists & inhibitors Trachea - physiology
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