Natural Antibody against Thomsen-Friedenreich Antigen in Sera of Patients with Carcinomas and Infectious Diseases

The levels of natural antibody against Thomsen-Friedenreich (TF) antigen in sera of patients with various cancers and infectious diseases were examined by an enzyme-linked immunosorbent assay (ELISA) and compared with those of healthy donors. The levels of antibody against TF antigen in sera of pati...

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Veröffentlicht in:	Journal of Nihon University School of Dentistry 1993, Vol.35(4), pp.241-243
Hauptverfasser:	KUSAMA, Masao, KUSAMA, Kaoru, HAYASHI, Satoru, SUNOUCHI, Tatsuto, CHU, Ling, MORO, Itaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neoplasm - blood Antigens, Neoplasm - blood Antigens, Tumor-Associated, Carbohydrate - immunology Carcinoma - immunology Dentistry Enzyme-Linked Immunosorbent Assay enzymelinked immunosorbent assay Humans infectious disease Isoantibodies - blood Isoantigens - immunology natural antibody Pneumonia - blood Pneumonia - immunology Pyelonephritis - blood Pyelonephritis - immunology Thomsen-Friedenreich antigen
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Zusammenfassung:	The levels of natural antibody against Thomsen-Friedenreich (TF) antigen in sera of patients with various cancers and infectious diseases were examined by an enzyme-linked immunosorbent assay (ELISA) and compared with those of healthy donors. The levels of antibody against TF antigen in sera of patients with adenocarcinomas such as gastric, pancreatic and colorectal cancers were lower than those of patients with hepatoma, pyelonephritis and pneumonia. These findings may reflect the expression of TF-antigen in adenocarcinoma tissues.
ISSN:	0029-0432 1884-2984
DOI:	10.2334/josnusd1959.35.241