The association between 'faint-positive' amniotic fluid acetylcholinesterase and fetal malformations

The association between 'faint-positive' amniotic fluid acetylcholinesterase and fetal malformations

The finding of a ‘faint‐positive’ acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out...

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Veröffentlicht in:Prenatal diagnosis 1993-11, Vol.13 (11), p.1071-1074
Hauptverfasser: Sadovsky, Yoel, Robbin, Michelle L., Crandall, Barbara F., Filly, Roy A., Golbus, Mitchell S.
Format: Artikel
Sprache:eng
Schlagworte:
'Faint-positive' acetylcholinesterase
acetylcholinesterase
Acetylcholinesterase - analysis
Amniocentesis
Amniotic Fluid - enzymology
Biological and medical sciences
Congenital Abnormalities - diagnosis
Female
Gastroschisis
Gynecology. Andrology. Obstetrics
Humans
malformation
man
Management. Prenatal diagnosis
Medical sciences
Predictive Value of Tests
Pregnancy
Pregnancy Trimester, Second
Pregnancy. Fetus. Placenta
prenatal diagnosis
Retrospective Studies
Risk Factors
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Zusammenfassung:The finding of a ‘faint‐positive’ acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out significant fetal malformations.
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.1970131113