Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

Here we examined the gas-phase structures of two tetrameric membrane protein complexes by ion mobility mass spectrometry. The collision cross sections measured for the ion channel are in accord with a compact configuration of subunits, suggesting that the native-like structure can be preserved under...

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Veröffentlicht in:	Journal of the American Chemical Society 2010-11, Vol.132 (44), p.15468-15470
Hauptverfasser:	Wang, Sheila C, Politis, Argyris, Di Bartolo, Natalie, Bavro, Vassiliy N, Tucker, Stephen J, Booth, Paula J, Barrera, Nelson P, Robinson, Carol V
Format:	Artikel
Sprache:	eng
Schlagworte:	Gases - chemistry Mass Spectrometry Membrane Proteins - chemistry Models, Molecular Multiprotein Complexes - chemistry Protein Subunits - chemistry
Online-Zugang:	Volltext
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