Copper‐Catalyzed SiB Bond Activation in Branched‐Selective Allylic Substitution of Linear Allylic Chlorides
The harder they come, the better they leave! Chloride is superior to all common leaving groups in the γ‐selective allylic substitution of linear precursors. This approach involves a novel copper‐catalyzed SiB bond activation (see scheme; γ/α≥98:2, 7 examples; Si=SiMe2Ph and B=Bpin with pin=pinacola...
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| Veröffentlicht in: | Angewandte Chemie (International ed.) 2010-11, Vol.49 (45), p.8513-8515 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The harder they come, the better they leave! Chloride is superior to all common leaving groups in the γ‐selective allylic substitution of linear precursors. This approach involves a novel copper‐catalyzed SiB bond activation (see scheme; γ/α≥98:2, 7 examples; Si=SiMe2Ph and B=Bpin with pin=pinacolato). |
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| ISSN: | 1433-7851 1521-3773 |
| DOI: | 10.1002/anie.201004658 |