Control of apoptotic DNA degradation

Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be critical for the activation and/or action of apoptogenic DNases.

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Veröffentlicht in:Nature cell biology 2000-04, Vol.2 (4), p.E63-E64
Hauptverfasser: Kroemer, Guido, Ferri, Karine F
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container_title Nature cell biology
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description Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be critical for the activation and/or action of apoptogenic DNases.
doi_str_mv 10.1038/35008692
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source MEDLINE; Nature Journals Online; SpringerLink Journals - AutoHoldings
subjects Animals
Apoptosis
Apoptosis - genetics
Biomedical and Life Sciences
Cancer Research
Cell Biology
Deoxyribonucleic acid
Developmental Biology
DNA
DNA Fragmentation - physiology
In Situ Nick-End Labeling
Life Sciences
Lysosomes
news-and-views
Phagocytes
Proteolysis
Stem Cells
Thymus Gland - cytology
title Control of apoptotic DNA degradation
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