Control of apoptotic DNA degradation

Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be critical for the activation and/or action of apoptogenic DNases.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature cell biology 2000-04, Vol.2 (4), p.E63-E64
Hauptverfasser:	Kroemer, Guido, Ferri, Karine F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - genetics Biomedical and Life Sciences Cancer Research Cell Biology Deoxyribonucleic acid Developmental Biology DNA DNA Fragmentation - physiology In Situ Nick-End Labeling Life Sciences Lysosomes news-and-views Phagocytes Proteolysis Stem Cells Thymus Gland - cytology
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Beschreibung
Zusammenfassung:	Apoptotic DNA degradation has been thought to be a cell-autonomous process. Recent evidence suggests that heterophagic recognition and engulfment of dying cells by non-apoptotic cells may be critical for the activation and/or action of apoptogenic DNases.
ISSN:	1465-7392 1476-4679
DOI:	10.1038/35008692