Composites made of flame-sprayed bioactive glass 45S5 and polymers: bioactivity and immediate sealing properties

Mohn D, Bruhin C, Luechinger NA, Stark WJ, Imfeld T, Zehnder M. Composites made of flame‐sprayed bioactive glass 45S5 and polymers: bioactivity and immediate sealing properties. International Endodontic Journal, 43, 1037–1046, 2010. Aim To engineer systems using polyisoprene (PI) or polycaprolactone (PCL) and nanometric bioactive glass 45S5 (BG) that could create a hydroxyapatite interface and thus ultimately make the use of an endodontic sealer unnecessary. Methodology Different composites using PI or PCL as matrix material were prepared with BG contents of up to 30 wt%. Unfilled PI and PCL, commercially available filled PI (Obtura gutta‐percha) and PCL pellets (Resilon) served as control materials. Bioactivity (in vitro precipitate formation in simulated body fluid) was investigated using scanning electron microscopy and X‐ray diffraction analysis. To test immediate sealing ability, simulated root canals were filled with heated materials, and dye leakage was assessed. Leakage was statistically compared between groups using Kruskal–Wallis analysis of variance followed by Mann–Whitney U tests and Bonferroni correction. The alpha‐type error was set at 0.05. Results Both composite systems revealed hydroxyapatite formation on their surface. This was not observed on control materials. Incorporating 30 wt% BG into PI and PCL significantly (P