Spontaneous globoid mineralization in the cerebellum of rats

Cerebellar globoid mineralization in two rats was examined by light and electron microscopy, and by X-ray microanalysis. The mineralization was round to oval in shape; it varied in size and was positive for the periodic acid-Schiff and von Kossa reactions. Ultrastructurally, a concentric lamellar st...

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Veröffentlicht in:	Journal of comparative pathology 1993-11, Vol.109 (4), p.447-451
Hauptverfasser:	Yanai, T., Masegi, T., Ueda, K., Manabe, J., Teranishi, M., Takaoka, M., Matsunuma, N., Fukuda, K., Goto, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - analysis Cerebellum - chemistry Cerebellum - diagnostic imaging Electron Probe Microanalysis - veterinary Female Male Microscopy, Electron - veterinary Minerals - analysis Phosphorus - analysis Radiography Rats Rats, Inbred F344
Online-Zugang:	Volltext
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Zusammenfassung:	Cerebellar globoid mineralization in two rats was examined by light and electron microscopy, and by X-ray microanalysis. The mineralization was round to oval in shape; it varied in size and was positive for the periodic acid-Schiff and von Kossa reactions. Ultrastructurally, a concentric lamellar structure was prominent in moderately electron-dense depositions. Elemental analysis revealed the presence of large amounts of calcium and phosphorus, and small amounts of zinc, potassium and aluminum.
ISSN:	0021-9975 1532-3129
DOI:	10.1016/S0021-9975(08)80308-8