Amacrine and horizontal cell dysfunction in adult ceroid-lipofuscinosis (Kufs disease) and anatomical correlates in the ovine model

Amacrine and horizontal cell dysfunction in adult ceroid-lipofuscinosis (Kufs disease) and anatomical correlates in the ovine model

Psychophysical examination of the visual performance of a patient with Kufs disease suggests abnormal functioning of the amacrine and horizontal cell systems of lateral inhibition. The sheep model offers insight into early patho-physiology of these cell types.

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Bibliographische Detailangaben
Veröffentlicht in:International ophthalmology 1985-04, Vol.8 (1), p.37-42
Hauptverfasser: Armstrong, D, Benedetto, M, Samuelson, D
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Disease Models, Animal
Female
Humans
Middle Aged
Neuronal Ceroid-Lipofuscinoses - pathology
Neuronal Ceroid-Lipofuscinoses - physiopathology
Photic Stimulation
Psychophysics - methods
Reference Values
Sheep
Vision Tests - instrumentation
Vision Tests - methods
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Beschreibung
Zusammenfassung:Psychophysical examination of the visual performance of a patient with Kufs disease suggests abnormal functioning of the amacrine and horizontal cell systems of lateral inhibition. The sheep model offers insight into early patho-physiology of these cell types.
ISSN:0165-5701
1573-2630
DOI:10.1007/BF00136460