Factors affecting electrospray ionization of effluents containing trifluoroacetic acid for high-performance liquid chromatography/mass spectrometry

A study optimized the performance of an electrospray ion source on a TSQ mass spectrometer in order to obtain high sensitivity and signal stability for the ionization of liquid chromatography effluents with mobile phases containing aqueous .1% TFA.

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Veröffentlicht in:Analytical chemistry (Washington) 1993-12, Vol.65 (23), p.3528-3533
Hauptverfasser: Eshraghi, Jamshid, Chowdhury, Swapan K
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container_title Analytical chemistry (Washington)
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creator Eshraghi, Jamshid
Chowdhury, Swapan K
description A study optimized the performance of an electrospray ion source on a TSQ mass spectrometer in order to obtain high sensitivity and signal stability for the ionization of liquid chromatography effluents with mobile phases containing aqueous .1% TFA.
doi_str_mv 10.1021/ac00071a035
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source MEDLINE; American Chemical Society (ACS) Journals
subjects Acids
Amino Acid Sequence
Analytical chemistry
Animals
Cattle
Chemistry
Chromatographic methods and physical methods associated with chromatography
Chromatography, High Pressure Liquid
Cytochrome c Group - chemistry
Exact sciences and technology
Horses
Ions
Mass Spectrometry
Molecular Sequence Data
Molecular Weight
Other chromatographic methods
Peptide Fragments - analysis
Peptides - analysis
Scientific imaging
Trifluoroacetic Acid - chemistry
title Factors affecting electrospray ionization of effluents containing trifluoroacetic acid for high-performance liquid chromatography/mass spectrometry
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