Sex Hormones as Protective Agents Against Radiation Mortality in Mice.
Summary 1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 day...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1954-05, Vol.86 (1), p.24-27 |
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| container_end_page | 27 |
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| container_issue | 1 |
| container_start_page | 24 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 86 |
| creator | Mirand, E. A. Hoffman, J. G. Reinhard, M. C. Goltz, H. L. |
| description | Summary
1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 days before or after the irradiation. 3. No toxic effects due to estrogens or androgens were seen in the administration of the hormones for 7 days after irradiation. |
| doi_str_mv | 10.3181/00379727-86-21001 |
| format | Article |
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1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 days before or after the irradiation. 3. No toxic effects due to estrogens or androgens were seen in the administration of the hormones for 7 days after irradiation.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-86-21001</identifier><identifier>PMID: 13177581</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>ANDROGENS ; Animals ; BENZOIC ACID ; BIOLOGY AND MEDICINE ; ESTERS ; ESTROGENS ; Gonadal Steroid Hormones - pharmacology ; HORMONES ; LETHAL DOSE ; MICE ; Old Medline ; Protective Agents ; RADIATION PROTECTION ; RADIATION SICKNESS ; SEX ; STEROIDS ; TESTOSTERONE ; TOXICITY ; X-Rays</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1954-05, Vol.86 (1), p.24-27</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-7dad6da24f6cd8694e2c6608b70b4a609b937db7ada41934fd4d1f2cc9b619b43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13177581$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/4364517$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Mirand, E. A.</creatorcontrib><creatorcontrib>Hoffman, J. G.</creatorcontrib><creatorcontrib>Reinhard, M. C.</creatorcontrib><creatorcontrib>Goltz, H. L.</creatorcontrib><creatorcontrib>Roswell Park Memorial Inst., Buffalo, N.Y</creatorcontrib><title>Sex Hormones as Protective Agents Against Radiation Mortality in Mice.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 days before or after the irradiation. 3. No toxic effects due to estrogens or androgens were seen in the administration of the hormones for 7 days after irradiation.</description><subject>ANDROGENS</subject><subject>Animals</subject><subject>BENZOIC ACID</subject><subject>BIOLOGY AND MEDICINE</subject><subject>ESTERS</subject><subject>ESTROGENS</subject><subject>Gonadal Steroid Hormones - pharmacology</subject><subject>HORMONES</subject><subject>LETHAL DOSE</subject><subject>MICE</subject><subject>Old Medline</subject><subject>Protective Agents</subject><subject>RADIATION PROTECTION</subject><subject>RADIATION SICKNESS</subject><subject>SEX</subject><subject>STEROIDS</subject><subject>TESTOSTERONE</subject><subject>TOXICITY</subject><subject>X-Rays</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1954</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KAzEURoMotlYfwI0MLtxNTSaZZLIsYq1QUfxZh0ySqSkzk5qkYt_e1Fbcubpc7vk-LgeAcwTHGFXoGkLMOCtYXtG8QBCiAzBEJS5zTDk_BMPtPd8CA3ASwjIBJSvoMRggjBgrKzQE0xfzlc2c71xvQiZD9uRdNCraT5NNFqaPIQ1p-xCzZ6mtjNb12YPzUbY2bjKbFqvM-BQcNbIN5mw_R-Btevt6M8vnj3f3N5N5rjAtY8601FTLgjRU6YpyYgpFKaxqBmsiKeQ1x0zXTGpJEMek0USjplCK1xTxmuARuNz1uhCtCMqmX9-V6_v0siCYkhKxBF3toJV3H2sTouhsUKZtZW_cOgiWuhhLckYA7UDlXQjeNGLlbSf9RiAotobFr2FRUfFjOGUu9uXrujP6L7FXmoDxDghyYcTSrX2fjPzT-A0GGoKj</recordid><startdate>195405</startdate><enddate>195405</enddate><creator>Mirand, E. A.</creator><creator>Hoffman, J. G.</creator><creator>Reinhard, M. C.</creator><creator>Goltz, H. L.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>195405</creationdate><title>Sex Hormones as Protective Agents Against Radiation Mortality in Mice.</title><author>Mirand, E. A. ; Hoffman, J. G. ; Reinhard, M. C. ; Goltz, H. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-7dad6da24f6cd8694e2c6608b70b4a609b937db7ada41934fd4d1f2cc9b619b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1954</creationdate><topic>ANDROGENS</topic><topic>Animals</topic><topic>BENZOIC ACID</topic><topic>BIOLOGY AND MEDICINE</topic><topic>ESTERS</topic><topic>ESTROGENS</topic><topic>Gonadal Steroid Hormones - pharmacology</topic><topic>HORMONES</topic><topic>LETHAL DOSE</topic><topic>MICE</topic><topic>Old Medline</topic><topic>Protective Agents</topic><topic>RADIATION PROTECTION</topic><topic>RADIATION SICKNESS</topic><topic>SEX</topic><topic>STEROIDS</topic><topic>TESTOSTERONE</topic><topic>TOXICITY</topic><topic>X-Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mirand, E. A.</creatorcontrib><creatorcontrib>Hoffman, J. G.</creatorcontrib><creatorcontrib>Reinhard, M. C.</creatorcontrib><creatorcontrib>Goltz, H. L.</creatorcontrib><creatorcontrib>Roswell Park Memorial Inst., Buffalo, N.Y</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mirand, E. A.</au><au>Hoffman, J. G.</au><au>Reinhard, M. C.</au><au>Goltz, H. L.</au><aucorp>Roswell Park Memorial Inst., Buffalo, N.Y</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sex Hormones as Protective Agents Against Radiation Mortality in Mice.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1954-05</date><risdate>1954</risdate><volume>86</volume><issue>1</issue><spage>24</spage><epage>27</epage><pages>24-27</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 days before or after the irradiation. 3. No toxic effects due to estrogens or androgens were seen in the administration of the hormones for 7 days after irradiation.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13177581</pmid><doi>10.3181/00379727-86-21001</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1954-05, Vol.86 (1), p.24-27 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76197700 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | ANDROGENS Animals BENZOIC ACID BIOLOGY AND MEDICINE ESTERS ESTROGENS Gonadal Steroid Hormones - pharmacology HORMONES LETHAL DOSE MICE Old Medline Protective Agents RADIATION PROTECTION RADIATION SICKNESS SEX STEROIDS TESTOSTERONE TOXICITY X-Rays |
| title | Sex Hormones as Protective Agents Against Radiation Mortality in Mice. |
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