Sex Hormones as Protective Agents Against Radiation Mortality in Mice.

Summary 1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 day...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1954-05, Vol.86 (1), p.24-27
Hauptverfasser:	Mirand, E. A., Hoffman, J. G., Reinhard, M. C., Goltz, H. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	ANDROGENS Animals BENZOIC ACID BIOLOGY AND MEDICINE ESTERS ESTROGENS Gonadal Steroid Hormones - pharmacology HORMONES LETHAL DOSE MICE Old Medline Protective Agents RADIATION PROTECTION RADIATION SICKNESS SEX STEROIDS TESTOSTERONE TOXICITY X-Rays
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Beschreibung
Zusammenfassung:	Summary 1. In dba mice diethylstilbestrol and estradiol benzoate reduce the acute radiation mortality. The androgens, testosterone propionate and depotestosterone cyclopentyl-propionate, afford no protection against acute lethal radiation dose. 2. The estrogens afford protection when given for 7 days before or after the irradiation. 3. No toxic effects due to estrogens or androgens were seen in the administration of the hormones for 7 days after irradiation.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-86-21001