Enzyme Inhibition

Enzyme Inhibition

Katchalski, Berger and Neumann 1 have recently described the inhibition of pepsin by polylysine, polyornithine and poly- p -amino-phenylalanine. We would suggest that this is not an isolated effect but is an example of a widespread non-specific action of high molecular weight polyelectrolytes on man...

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Veröffentlicht in:Nature (London) 1954-06, Vol.173 (4416), p.1190-1190
Hauptverfasser: SPENSLEY, P. C, ROGERS, H. J
Format: Artikel
Sprache:eng
Schlagworte:
Biochemical Phenomena
Enzymes
Humanities and Social Sciences
letter
multidisciplinary
Old Medline
Science
Science (multidisciplinary)
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Zusammenfassung:Katchalski, Berger and Neumann 1 have recently described the inhibition of pepsin by polylysine, polyornithine and poly- p -amino-phenylalanine. We would suggest that this is not an isolated effect but is an example of a widespread non-specific action of high molecular weight polyelectrolytes on many enzymes.
ISSN:0028-0836
1476-4687
DOI:10.1038/1731190a0