Kinetoplast DNA from Trypanosoma vivax and T. congolense
We have analysed kinetoplast DNA (kDNA) of the African trypanosomes Trypanosoma vivax and T. congolense. The maxi-circles from these organisms resemble those of T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA-DNA hybridization. The kDNA n...
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| Veröffentlicht in: | Molecular and biochemical parasitology 1985-05, Vol.15 (2), p.129-142 |
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| container_title | Molecular and biochemical parasitology |
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| creator | Borst, Piet Fase-Fowler, Francesca Weijers, Peter J. Barry, J.Dave Tetley, Laurence Vickerman, Keith |
| description | We have analysed kinetoplast DNA (kDNA) of the African trypanosomes
Trypanosoma vivax and
T. congolense. The maxi-circles from these organisms resemble those of
T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA-DNA hybridization. The kDNA networks of
T. vivax have three distinguishing features: they contain the highest maxi-circle concentration of any kDNA (at least twice that of
T. brucei); they contain the smallest mini-circles (465 bp) yet found thusfar and the width of the kDNA nucleoid in thin sections is correspondingly small (55 nm against 91 nm for
T. brucei); they contain a substantial fraction of mini-circle dimers. |
| doi_str_mv | 10.1016/0166-6851(85)90114-8 |
| format | Article |
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Trypanosoma vivax and
T. congolense. The maxi-circles from these organisms resemble those of
T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA-DNA hybridization. The kDNA networks of
T. vivax have three distinguishing features: they contain the highest maxi-circle concentration of any kDNA (at least twice that of
T. brucei); they contain the smallest mini-circles (465 bp) yet found thusfar and the width of the kDNA nucleoid in thin sections is correspondingly small (55 nm against 91 nm for
T. brucei); they contain a substantial fraction of mini-circle dimers.</description><identifier>ISSN: 0166-6851</identifier><identifier>EISSN: 1872-9428</identifier><identifier>DOI: 10.1016/0166-6851(85)90114-8</identifier><identifier>PMID: 2989683</identifier><identifier>CODEN: MBIPDP</identifier><language>eng</language><publisher>Shannon: Elsevier B.V</publisher><subject>Animals ; Biochemistry. Physiology. Immunology. Molecular biology ; Biological and medical sciences ; DNA, Circular - analysis ; DNA, Kinetoplast ; Electrophoresis, Agar Gel ; Fundamental and applied biological sciences. Psychology ; Human protozoal diseases ; Infectious diseases ; Kinetoplast DNA ; Maxi-circle ; Medical sciences ; Mini-circle ; Parasitic diseases ; Protozoa ; Protozoal diseases ; Tropical medicine ; Trypanosoma - analysis ; Trypanosoma - ultrastructure ; Trypanosoma congolense ; Trypanosoma congolense - analysis ; Trypanosoma congolense - ultrastructure ; Trypanosoma vivax ; Trypanosomiasis</subject><ispartof>Molecular and biochemical parasitology, 1985-05, Vol.15 (2), p.129-142</ispartof><rights>1985</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c301t-d7ce771d20a62e6e9bbb903bb68b3bc2988fa2b9ecef897617cb1f9ffea247dd3</citedby><cites>FETCH-LOGICAL-c301t-d7ce771d20a62e6e9bbb903bb68b3bc2988fa2b9ecef897617cb1f9ffea247dd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0166685185901148$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9252073$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2989683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Borst, Piet</creatorcontrib><creatorcontrib>Fase-Fowler, Francesca</creatorcontrib><creatorcontrib>Weijers, Peter J.</creatorcontrib><creatorcontrib>Barry, J.Dave</creatorcontrib><creatorcontrib>Tetley, Laurence</creatorcontrib><creatorcontrib>Vickerman, Keith</creatorcontrib><title>Kinetoplast DNA from Trypanosoma vivax and T. congolense</title><title>Molecular and biochemical parasitology</title><addtitle>Mol Biochem Parasitol</addtitle><description>We have analysed kinetoplast DNA (kDNA) of the African trypanosomes
Trypanosoma vivax and
T. congolense. The maxi-circles from these organisms resemble those of
T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA-DNA hybridization. The kDNA networks of
T. vivax have three distinguishing features: they contain the highest maxi-circle concentration of any kDNA (at least twice that of
T. brucei); they contain the smallest mini-circles (465 bp) yet found thusfar and the width of the kDNA nucleoid in thin sections is correspondingly small (55 nm against 91 nm for
T. brucei); they contain a substantial fraction of mini-circle dimers.</description><subject>Animals</subject><subject>Biochemistry. Physiology. Immunology. Molecular biology</subject><subject>Biological and medical sciences</subject><subject>DNA, Circular - analysis</subject><subject>DNA, Kinetoplast</subject><subject>Electrophoresis, Agar Gel</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Human protozoal diseases</subject><subject>Infectious diseases</subject><subject>Kinetoplast DNA</subject><subject>Maxi-circle</subject><subject>Medical sciences</subject><subject>Mini-circle</subject><subject>Parasitic diseases</subject><subject>Protozoa</subject><subject>Protozoal diseases</subject><subject>Tropical medicine</subject><subject>Trypanosoma - analysis</subject><subject>Trypanosoma - ultrastructure</subject><subject>Trypanosoma congolense</subject><subject>Trypanosoma congolense - analysis</subject><subject>Trypanosoma congolense - ultrastructure</subject><subject>Trypanosoma vivax</subject><subject>Trypanosomiasis</subject><issn>0166-6851</issn><issn>1872-9428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EKuXxByBlgRAsAraT-LFBqniLCjZlbdnOGBklcbHTCv6elFZdshjNYs69Gh2ETgi-Ipiw62FYzkRFLkR1KTEhZS520JgITnNZUrGLxltkHx2k9IkxrjhjIzSiUkgmijESL76DPswbnfrs7nWSuRjabBZ_5roLKbQ6W_ql_s50V2ezq8yG7iM00CU4QntONwmON_sQvT_cz26f8unb4_PtZJrbApM-r7kFzklNsWYUGEhjjMSFMUyYwtjhD-E0NRIsOCE5I9wa4qRzoGnJ67o4ROfr3nkMXwtIvWp9stA0uoOwSGqIiKrEbADLNWhjSCmCU_PoWx1_FMFqJUytbKiVDSUq9SdMiSF2uulfmBbqbWhjaLifbe46Wd24qDvr0xaTtKKYr7CbNQaDi6WHqJL10FmofQTbqzr4___4BZaPhrw</recordid><startdate>198505</startdate><enddate>198505</enddate><creator>Borst, Piet</creator><creator>Fase-Fowler, Francesca</creator><creator>Weijers, Peter J.</creator><creator>Barry, J.Dave</creator><creator>Tetley, Laurence</creator><creator>Vickerman, Keith</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198505</creationdate><title>Kinetoplast DNA from Trypanosoma vivax and T. congolense</title><author>Borst, Piet ; Fase-Fowler, Francesca ; Weijers, Peter J. ; Barry, J.Dave ; Tetley, Laurence ; Vickerman, Keith</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c301t-d7ce771d20a62e6e9bbb903bb68b3bc2988fa2b9ecef897617cb1f9ffea247dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Animals</topic><topic>Biochemistry. Physiology. Immunology. Molecular biology</topic><topic>Biological and medical sciences</topic><topic>DNA, Circular - analysis</topic><topic>DNA, Kinetoplast</topic><topic>Electrophoresis, Agar Gel</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Human protozoal diseases</topic><topic>Infectious diseases</topic><topic>Kinetoplast DNA</topic><topic>Maxi-circle</topic><topic>Medical sciences</topic><topic>Mini-circle</topic><topic>Parasitic diseases</topic><topic>Protozoa</topic><topic>Protozoal diseases</topic><topic>Tropical medicine</topic><topic>Trypanosoma - analysis</topic><topic>Trypanosoma - ultrastructure</topic><topic>Trypanosoma congolense</topic><topic>Trypanosoma congolense - analysis</topic><topic>Trypanosoma congolense - ultrastructure</topic><topic>Trypanosoma vivax</topic><topic>Trypanosomiasis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Borst, Piet</creatorcontrib><creatorcontrib>Fase-Fowler, Francesca</creatorcontrib><creatorcontrib>Weijers, Peter J.</creatorcontrib><creatorcontrib>Barry, J.Dave</creatorcontrib><creatorcontrib>Tetley, Laurence</creatorcontrib><creatorcontrib>Vickerman, Keith</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular and biochemical parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Borst, Piet</au><au>Fase-Fowler, Francesca</au><au>Weijers, Peter J.</au><au>Barry, J.Dave</au><au>Tetley, Laurence</au><au>Vickerman, Keith</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Kinetoplast DNA from Trypanosoma vivax and T. congolense</atitle><jtitle>Molecular and biochemical parasitology</jtitle><addtitle>Mol Biochem Parasitol</addtitle><date>1985-05</date><risdate>1985</risdate><volume>15</volume><issue>2</issue><spage>129</spage><epage>142</epage><pages>129-142</pages><issn>0166-6851</issn><eissn>1872-9428</eissn><coden>MBIPDP</coden><abstract>We have analysed kinetoplast DNA (kDNA) of the African trypanosomes
Trypanosoma vivax and
T. congolense. The maxi-circles from these organisms resemble those of
T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA-DNA hybridization. The kDNA networks of
T. vivax have three distinguishing features: they contain the highest maxi-circle concentration of any kDNA (at least twice that of
T. brucei); they contain the smallest mini-circles (465 bp) yet found thusfar and the width of the kDNA nucleoid in thin sections is correspondingly small (55 nm against 91 nm for
T. brucei); they contain a substantial fraction of mini-circle dimers.</abstract><cop>Shannon</cop><pub>Elsevier B.V</pub><pmid>2989683</pmid><doi>10.1016/0166-6851(85)90114-8</doi><tpages>14</tpages></addata></record> |
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| ispartof | Molecular and biochemical parasitology, 1985-05, Vol.15 (2), p.129-142 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences DNA, Circular - analysis DNA, Kinetoplast Electrophoresis, Agar Gel Fundamental and applied biological sciences. Psychology Human protozoal diseases Infectious diseases Kinetoplast DNA Maxi-circle Medical sciences Mini-circle Parasitic diseases Protozoa Protozoal diseases Tropical medicine Trypanosoma - analysis Trypanosoma - ultrastructure Trypanosoma congolense Trypanosoma congolense - analysis Trypanosoma congolense - ultrastructure Trypanosoma vivax Trypanosomiasis |
| title | Kinetoplast DNA from Trypanosoma vivax and T. congolense |
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