Synthesis, anticonvulsant and antimicrobial activities of certain new furochromones

Some new substituted thiazolidinones, thioimidazolidinones and thiazolines have been synthesized from N1-substituted N2-(4-hydroxy-7-methyl-5H-furo[3,2-g] [1]benzopyran-5-on-9-yl)thioureas and monochloroacetic acid or alpha-halocarbonyl compounds. Some representative examples were tested for their a...

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Veröffentlicht in:	Pharmazie 1993-11, Vol.48 (11), p.808-811
Hauptverfasser:	RAGAB, F. A, HUSSEIN, M. M, HANA, M. M, HASSAN, G. S, KENAWY, S. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology Anticonvulsants - chemical synthesis Anticonvulsants - pharmacology Anticonvulsants. Antiepileptics. Antiparkinson agents Bacteria - drug effects Biological and medical sciences Chromones - chemical synthesis Chromones - pharmacology Fungi - drug effects Magnetic Resonance Spectroscopy Male Medical sciences Mice Microbial Sensitivity Tests Neuropharmacology Pentylenetetrazole - antagonists & inhibitors Pharmacology. Drug treatments Spectrophotometry, Infrared
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Zusammenfassung:	Some new substituted thiazolidinones, thioimidazolidinones and thiazolines have been synthesized from N1-substituted N2-(4-hydroxy-7-methyl-5H-furo[3,2-g] [1]benzopyran-5-on-9-yl)thioureas and monochloroacetic acid or alpha-halocarbonyl compounds. Some representative examples were tested for their anticonvulsant and antimicrobial activities.
ISSN:	0031-7144