Congenital diaphragmatic hernia in the Brachmann-de Lange syndrome

We present 12 children with typical Brachmann‐de Lange syndrome and congenital diaphragmatic hernia. Affected children were more likely to be of low birth weight and to have major upper limb malformations. Hernia repair was attempted in 4 of these children, and only one survived past 12 months, Newborn infants with congenital diaphragmatic hernia should be examined carefully for evidence of the Brachmann‐de Lange syndrome because diagnosis of thes condition may influence their clinical management and prognosis. © 1993 Wiley‐Liss, Inc.