Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo
1. 1. The effect of ethanol upon the oxidation of leucine by the rat in vivo was determined. 2. 2. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20% v v solution as drinking water for 28 days). 3. 3. Ethanol administered acutely (8 g kg 0.73) signi...
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| Veröffentlicht in: | International journal of biochemistry 1985, Vol.17 (2), p.187-193 |
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| container_title | International journal of biochemistry |
| container_volume | 17 |
| creator | Ward, Leigh C. Carrington, Lyle E. Daly, Ross |
| description | 1.
1. The effect of ethanol upon the oxidation of leucine by the rat
in vivo was determined.
2.
2. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20%
v
v
solution as drinking water for 28 days).
3.
3. Ethanol administered acutely (8 g kg
0.73) significantly decreased leucine oxidation by the rat
in vivo. This decrease appeared to be independent of a more general depression of oxidation metabolism.
4.
4. Decrease in leucine oxidation by ethanol is discussed in relation to the regulation of tissue leucine pool sizes
in vivo. |
| doi_str_mv | 10.1016/0020-711X(85)90113-2 |
| format | Article |
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1. The effect of ethanol upon the oxidation of leucine by the rat
in vivo was determined.
2.
2. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20%
v
v
solution as drinking water for 28 days).
3.
3. Ethanol administered acutely (8 g kg
0.73) significantly decreased leucine oxidation by the rat
in vivo. This decrease appeared to be independent of a more general depression of oxidation metabolism.
4.
4. Decrease in leucine oxidation by ethanol is discussed in relation to the regulation of tissue leucine pool sizes
in vivo.</description><identifier>ISSN: 0020-711X</identifier><identifier>DOI: 10.1016/0020-711X(85)90113-2</identifier><identifier>PMID: 3924678</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Aminoisobutyric Acids - metabolism ; Animals ; Carbon Dioxide - analysis ; Carbon Radioisotopes ; Ethanol - blood ; Ethanol - metabolism ; Ethanol - pharmacology ; Kinetics ; Leucine - metabolism ; Male ; Oxidation-Reduction ; Rats ; Rats, Inbred Strains</subject><ispartof>International journal of biochemistry, 1985, Vol.17 (2), p.187-193</ispartof><rights>1985</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c303t-883f046f81066dfee77c7d44cae9315f057b744e5f7fc1d998098384768f3a2d3</citedby><cites>FETCH-LOGICAL-c303t-883f046f81066dfee77c7d44cae9315f057b744e5f7fc1d998098384768f3a2d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3924678$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ward, Leigh C.</creatorcontrib><creatorcontrib>Carrington, Lyle E.</creatorcontrib><creatorcontrib>Daly, Ross</creatorcontrib><title>Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo</title><title>International journal of biochemistry</title><addtitle>Int J Biochem</addtitle><description>1.
1. The effect of ethanol upon the oxidation of leucine by the rat
in vivo was determined.
2.
2. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20%
v
v
solution as drinking water for 28 days).
3.
3. Ethanol administered acutely (8 g kg
0.73) significantly decreased leucine oxidation by the rat
in vivo. This decrease appeared to be independent of a more general depression of oxidation metabolism.
4.
4. Decrease in leucine oxidation by ethanol is discussed in relation to the regulation of tissue leucine pool sizes
in vivo.</description><subject>Aminoisobutyric Acids - metabolism</subject><subject>Animals</subject><subject>Carbon Dioxide - analysis</subject><subject>Carbon Radioisotopes</subject><subject>Ethanol - blood</subject><subject>Ethanol - metabolism</subject><subject>Ethanol - pharmacology</subject><subject>Kinetics</subject><subject>Leucine - metabolism</subject><subject>Male</subject><subject>Oxidation-Reduction</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><issn>0020-711X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9KwzAcx3NQdE7fQCEn0UNn0qRNehFkzDkYeFHwFrLkFxbp2pm0w918CJ_QJ7FzYwcPevrB998PPgidUzKghOY3hKQkEZS-XMnsuiCUsiQ9QL29fIxOYnwlhBaS0yN0xIqU50L20HjUzHVVl1hXFpfQGl8Brt-91Y2vq6-Pz8kAT3_LeLbGzRxw0A32FV75VX2KDp0uI5ztbh8934-ehg_J9HE8Gd5NE8MIaxIpmSM8d5KSPLcOQAgjLOdGQ8Fo5kgmZoJzyJxwhtqikKSQTHKRS8d0alkfXW53l6F-ayE2auGjgbLUFdRtVCKneUZY8W-Q8jRjaUa7IN8GTahjDODUMviFDmtFidrAVRuKakNRyUz9wFVpV7vY7bezBdh9aUe282-3PnQ0Vh6CisZDZcD6AKZRtvZ_P_gGsqOKYw</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Ward, Leigh C.</creator><creator>Carrington, Lyle E.</creator><creator>Daly, Ross</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>1985</creationdate><title>Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo</title><author>Ward, Leigh C. ; Carrington, Lyle E. ; Daly, Ross</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c303t-883f046f81066dfee77c7d44cae9315f057b744e5f7fc1d998098384768f3a2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Aminoisobutyric Acids - metabolism</topic><topic>Animals</topic><topic>Carbon Dioxide - analysis</topic><topic>Carbon Radioisotopes</topic><topic>Ethanol - blood</topic><topic>Ethanol - metabolism</topic><topic>Ethanol - pharmacology</topic><topic>Kinetics</topic><topic>Leucine - metabolism</topic><topic>Male</topic><topic>Oxidation-Reduction</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><toplevel>online_resources</toplevel><creatorcontrib>Ward, Leigh C.</creatorcontrib><creatorcontrib>Carrington, Lyle E.</creatorcontrib><creatorcontrib>Daly, Ross</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ward, Leigh C.</au><au>Carrington, Lyle E.</au><au>Daly, Ross</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo</atitle><jtitle>International journal of biochemistry</jtitle><addtitle>Int J Biochem</addtitle><date>1985</date><risdate>1985</risdate><volume>17</volume><issue>2</issue><spage>187</spage><epage>193</epage><pages>187-193</pages><issn>0020-711X</issn><abstract>1.
1. The effect of ethanol upon the oxidation of leucine by the rat
in vivo was determined.
2.
2. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20%
v
v
solution as drinking water for 28 days).
3.
3. Ethanol administered acutely (8 g kg
0.73) significantly decreased leucine oxidation by the rat
in vivo. This decrease appeared to be independent of a more general depression of oxidation metabolism.
4.
4. Decrease in leucine oxidation by ethanol is discussed in relation to the regulation of tissue leucine pool sizes
in vivo.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>3924678</pmid><doi>10.1016/0020-711X(85)90113-2</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0020-711X |
| ispartof | International journal of biochemistry, 1985, Vol.17 (2), p.187-193 |
| issn | 0020-711X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76165039 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Aminoisobutyric Acids - metabolism Animals Carbon Dioxide - analysis Carbon Radioisotopes Ethanol - blood Ethanol - metabolism Ethanol - pharmacology Kinetics Leucine - metabolism Male Oxidation-Reduction Rats Rats, Inbred Strains |
| title | Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo |
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