Chemotherapy of Experimental Anthrax Infections

Chemotherapy of Experimental Anthrax Infections

Streptomycin, penicillin and sodium sulfadiazine were tested for efficacy in experimental anthrax infections in mice. Maximal survival rates of 92 per cent were obtained with streptomycin, 58 per cent with penicillin, and only 5 per cent with sulfadiazine. Latent infections were not present in treat...

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Veröffentlicht in:The Journal of immunology (1950) 1946-08, Vol.53 (4), p.371-379
Hauptverfasser: Miller, Edward S, Scott, Earl B, Noe, Herbert A, Madin, Stewart H, Henley, Thomas F
Format: Artikel
Sprache:eng
Schlagworte:
Anthrax - therapy
Humans
Old Medline
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Zusammenfassung:Streptomycin, penicillin and sodium sulfadiazine were tested for efficacy in experimental anthrax infections in mice. Maximal survival rates of 92 per cent were obtained with streptomycin, 58 per cent with penicillin, and only 5 per cent with sulfadiazine. Latent infections were not present in treated animals surviving 28 days after inoculation with lethal doses of B. anthracis spores.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.53.4.371