Immunoregulation During Acute Infection with Epstein-Barr Virus: Dynamics of Interferon and 2′,5′-Oligoadenylate Synthetase Activity

Immunoregulation during acute infection with Epstein-Barr virus (EBV) is incompletely understood, although species of interferon (IFN) may be important immunoregulatory molecules. IFN, 2′,5′-oligoadenylate (2′,5′-A) synthetase (an IFN-induced enzyme), T and natural killer cell subsets, and natural a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 1985-06, Vol.151 (6), p.1109-1115
Hauptverfasser:	Brewster, Frank E., Byron, Kevin S., Sullivan, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	2',5'-Oligoadenylate Synthetase - analysis Adolescent Adult Antigens, Surface - analysis B lymphocytes Biological and medical sciences Cell lines Cytotoxicity Cytotoxicity, Immunologic Epstein Barr virus infections Epstein-Barr virus Female Herpesvirus 4, Human Human viral diseases Humans Infectious diseases Infectious Mononucleosis - enzymology Infectious Mononucleosis - immunology Interferons Interferons - analysis Killer Cells, Natural - immunology Male Medical sciences Miscellaneous Monocytes - enzymology Natural killer cells Natural killer T cells Original Articles PC12 cells T lymphocytes T-Lymphocytes - immunology Tropical viral diseases Viral cardiopathies Viral diseases Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Immunoregulation during acute infection with Epstein-Barr virus (EBV) is incompletely understood, although species of interferon (IFN) may be important immunoregulatory molecules. IFN, 2′,5′-oligoadenylate (2′,5′-A) synthetase (an IFN-induced enzyme), T and natural killer cell subsets, and natural and anomalous killer cell functions were studied systematically during acute infectious mononucleosis. Serum IFN was not detected (
ISSN:	0022-1899 1537-6613
DOI:	10.1093/infdis/151.6.1109