STRUCTURAL STUDY OF A NEW ANTITUMOR ANTIBIOTIC, KAZUSAMYCIN

The structure of a new antitumor antibiotic, kazusamycin produced by Streptomyces sp. No. 81-484, was determined on the basis of its spectral and chemical properties. Kazusamycin has a structure characteristic of an unsaturated, branched-chain fatty acid with a terminal δ-lactone ring.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1985, Vol.38(2), pp.220-223
Hauptverfasser:	KOMIYAMA, KANKI, OKADA, KENJI, OKA, HIROFUMI, TOMISAKA, SHIGERU, MIYANO, TETSUJI, FUNAYAMA, SHINJI, UMEZAWA, IWAO
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antineoplastic - isolation & purification Biological and medical sciences Chemical Phenomena Chemistry Fatty Acids, Unsaturated - isolation & purification General pharmacology Lactones - isolation & purification Medical sciences Peptide Chain Termination, Translational Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Streptomyces Streptomyces - metabolism Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The structure of a new antitumor antibiotic, kazusamycin produced by Streptomyces sp. No. 81-484, was determined on the basis of its spectral and chemical properties. Kazusamycin has a structure characteristic of an unsaturated, branched-chain fatty acid with a terminal δ-lactone ring.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.38.220