In Vitro Response of Bone-Derived Cells and Tissues to the Fine Rahmen Surface Layer of a Carbon Implant

Carbon sheets made of fine meshwork identical with the surface layer of the FRS implant were prepared as specimens and bone explants were cultured on the specimen aimed at observing the in vitro response of the bone tissue to the carbon fine Rahmen surface structure. The findings are summarized below. 1. The cells passed through the fine Rahmen surface structure layer of carbon in a short period of time. 2. The carbon fiber served as a scaffold for attachment of the cells. 3. The bone-derived cells proliferated to form a tissue matrix within the spaces of the fine Rahmen surface structure of the carbon. 4. Collagen fibers became either attached to the carbon fibers or interwoven with the carbon fibers or both, thus giving an anchoring effect. 5. The fine Rahmen surface structure of the carbon was buried in and unified with the tissue grown from bone.