Hypothesis to explain the association between hypocalciuria and low circulating 1, 25-dihydroxyvitamin D levels in preeclampsia

A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible...

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Veröffentlicht in:Medical hypotheses 1993-09, Vol.41 (3), p.239-243
Hauptverfasser: Bourges, H., Halhali, A.
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container_title Medical hypotheses
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creator Bourges, H.
Halhali, A.
description A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible reduction in the synthesis of insulin-like growth factor I.
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subjects Biological and medical sciences
Calcitriol - blood
Calcium - pharmacokinetics
Calcium - urine
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Homeostasis
Humans
Insulin-Like Growth Factor I - biosynthesis
Intestinal Absorption
Medical sciences
Models, Biological
Placenta - metabolism
Placental Lactogen - blood
Pre-Eclampsia - blood
Pre-Eclampsia - urine
Pregnancy
Pregnancy. Fetus. Placenta
title Hypothesis to explain the association between hypocalciuria and low circulating 1, 25-dihydroxyvitamin D levels in preeclampsia
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