Hypothesis to explain the association between hypocalciuria and low circulating 1, 25-dihydroxyvitamin D levels in preeclampsia
A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible...
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Veröffentlicht in: | Medical hypotheses 1993-09, Vol.41 (3), p.239-243 |
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description | A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible reduction in the synthesis of insulin-like growth factor I. |
doi_str_mv | 10.1016/0306-9877(93)90238-L |
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Andrology. Obstetrics ; Homeostasis ; Humans ; Insulin-Like Growth Factor I - biosynthesis ; Intestinal Absorption ; Medical sciences ; Models, Biological ; Placenta - metabolism ; Placental Lactogen - blood ; Pre-Eclampsia - blood ; Pre-Eclampsia - urine ; Pregnancy ; Pregnancy. Fetus. 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Andrology. Obstetrics</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Insulin-Like Growth Factor I - biosynthesis</subject><subject>Intestinal Absorption</subject><subject>Medical sciences</subject><subject>Models, Biological</subject><subject>Placenta - metabolism</subject><subject>Placental Lactogen - blood</subject><subject>Pre-Eclampsia - blood</subject><subject>Pre-Eclampsia - urine</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. 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Andrology. Obstetrics</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Insulin-Like Growth Factor I - biosynthesis</topic><topic>Intestinal Absorption</topic><topic>Medical sciences</topic><topic>Models, Biological</topic><topic>Placenta - metabolism</topic><topic>Placental Lactogen - blood</topic><topic>Pre-Eclampsia - blood</topic><topic>Pre-Eclampsia - urine</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. 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subjects | Biological and medical sciences Calcitriol - blood Calcium - pharmacokinetics Calcium - urine Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Homeostasis Humans Insulin-Like Growth Factor I - biosynthesis Intestinal Absorption Medical sciences Models, Biological Placenta - metabolism Placental Lactogen - blood Pre-Eclampsia - blood Pre-Eclampsia - urine Pregnancy Pregnancy. Fetus. Placenta |
title | Hypothesis to explain the association between hypocalciuria and low circulating 1, 25-dihydroxyvitamin D levels in preeclampsia |
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