Hypothesis to explain the association between hypocalciuria and low circulating 1, 25-dihydroxyvitamin D levels in preeclampsia

A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible...

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Veröffentlicht in:	Medical hypotheses 1993-09, Vol.41 (3), p.239-243
Hauptverfasser:	Bourges, H., Halhali, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcitriol - blood Calcium - pharmacokinetics Calcium - urine Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Homeostasis Humans Insulin-Like Growth Factor I - biosynthesis Intestinal Absorption Medical sciences Models, Biological Placenta - metabolism Placental Lactogen - blood Pre-Eclampsia - blood Pre-Eclampsia - urine Pregnancy Pregnancy. Fetus. Placenta
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Beschreibung
Zusammenfassung:	A hypothesis is presented according to which the hypocalciuria in preeclamptic women is due to a decreased efficiency of intestinal calcium absorption as a consequence of diminished placental synthesis of 1,25-dihydroxyvitamin D related to lower circulating placental lactogen level and/or a possible reduction in the synthesis of insulin-like growth factor I.
ISSN:	0306-9877 1532-2777
DOI:	10.1016/0306-9877(93)90238-L