Controlled trial of treatment of recurrent spontaneous abortion by immunisation with paternal cells

In a paired sequential double-blind trial of immunological treatment of recurrent spontaneous abortion successful outcome of the next pregnancy was significantly more common in women injected with purified lymphocytes prepared from their husbands' blood than in those injected with their own lym...

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Veröffentlicht in:	The Lancet (British edition) 1985-04, Vol.1 (8435), p.941-943
Hauptverfasser:	Mowbray, J F, Gibbings, C, Liddell, H, Reginald, P W, Underwood, J L, Beard, R W
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - immunology Abortion, Habitual - prevention & control Antilymphocyte Serum - immunology Clinical Trials as Topic Double-Blind Method Female Humans Immunization Infant, Newborn Lymphocytes - immunology Male Pregnancy
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Zusammenfassung:	In a paired sequential double-blind trial of immunological treatment of recurrent spontaneous abortion successful outcome of the next pregnancy was significantly more common in women injected with purified lymphocytes prepared from their husbands' blood than in those injected with their own lymphocytes. 17 of 22 women given paternal cells had successful pregnancies, compared with 10 of 27 given their own cells.
ISSN:	0140-6736