Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast

The MATα2 protein of budding yeast represses a set of genes; if the MATa1 protein is also present, a further set of genes is repressed. DNA sequence comparisons reveal a 20-base pair ‘operator’ sequence that is present in genes repressed by a1/α2 . A related, but distinct, sequence is found in genes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1985-04, Vol.314 (6012), p.598-603
Hauptverfasser:	Miller, Allan M, MacKay, Vivian L, Nasmyth, Kim A
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences DNA, Fungal - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genes, Fungal Humanities and Social Sciences Mating Factor Molecular and cellular biology Molecular genetics multidisciplinary Peptides - genetics Promoter Regions, Genetic Repressor Proteins - genetics Saccharomyces cerevisiae - genetics Science Science (multidisciplinary) Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The MATα2 protein of budding yeast represses a set of genes; if the MATa1 protein is also present, a further set of genes is repressed. DNA sequence comparisons reveal a 20-base pair ‘operator’ sequence that is present in genes repressed by a1/α2 . A related, but distinct, sequence is found in genes repressed by α2 alone.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/314598a0