The effects of gastric inhibitory polypeptide (GIP) on the release of anterior pituitary hormones

Several members of the secretin family of hormones have been demonstrated to alter anterior pituitary hormone secretion. Here we report the action of gastric inhibitory polypeptide (GIP) on gonadotropin and somatotropin release. Intraventricular injection of 1 μg (0.2 nmole) GIP (2.5 μl) produced a...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1985-01, Vol.6 (1), p.115-119
Hauptverfasser:	Ottlecz, Anna, Samson, Willis K., McCann, Samuel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Castration Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Gastric inhibitory polypeptide Gastric Inhibitory Polypeptide - administration & dosage Gastric Inhibitory Polypeptide - pharmacology Gastrointestinal Hormones - pharmacology GIP and pituitary hormone release Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis Injections, Intraventricular Pituitary Gland, Anterior - drug effects Pituitary Gland, Anterior - metabolism Pituitary Hormones, Anterior - metabolism Rats Rats, Inbred Strains Secretory Rate - drug effects Vertebrates: endocrinology
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Zusammenfassung:	Several members of the secretin family of hormones have been demonstrated to alter anterior pituitary hormone secretion. Here we report the action of gastric inhibitory polypeptide (GIP) on gonadotropin and somatotropin release. Intraventricular injection of 1 μg (0.2 nmole) GIP (2.5 μl) produced a significant decrease in plasma FSH at 30 ( p
ISSN:	0196-9781 1873-5169
DOI:	10.1016/0196-9781(85)90086-5