Possible reversal of ageing and other mitochondrial deficiencies through retroviral transfection of mitochondrially encoded proteins to the nucleus

This paper puts forward the hypothesis that ageing processes and a number of mitochondrially related diseases can be reversed or cured respectively. It briefly discusses the role of the mitochondrial genome in ageing and a number of inherited and age-related diseases. A rationale is then suggested which involves the utilization of retroviruses in translocating mitochondrial encoded proteins to the nucleus. Finally a number of problems which may arise from this translocation are discussed.