Philadelphia-positive T-acute lymphoblastic leukemia
A case of typical T-acute lymphoblastic leukemia (T-ALL) is reported in which, at diagnosis, 100% of bone marrow metaphases showed a Philadelphia (Ph) translocation, t(9;22). These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is...
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| Veröffentlicht in: | Cancer genetics and cytogenetics 1985-04, Vol.16 (4), p.297-300 |
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| container_issue | 4 |
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| container_title | Cancer genetics and cytogenetics |
| container_volume | 16 |
| creator | Louwagie, Andries Criel, Arnold Verfaillie, C.M. Valcke, Y.J. Lamberts, H. Hidajat, M. Mecucci, Cristina Van Den Berghe, Herman |
| description | A case of typical T-acute lymphoblastic leukemia (T-ALL) is reported in which, at diagnosis, 100% of bone marrow metaphases showed a Philadelphia (Ph) translocation, t(9;22). These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is discussed. |
| doi_str_mv | 10.1016/0165-4608(85)90236-5 |
| format | Article |
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These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is discussed.</description><identifier>ISSN: 0165-4608</identifier><identifier>EISSN: 1873-4456</identifier><identifier>DOI: 10.1016/0165-4608(85)90236-5</identifier><identifier>PMID: 3872163</identifier><identifier>CODEN: CGCYDF</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Chromosomes, Human, 21-22 and Y ; Chromosomes, Human, 6-12 and X ; Hematologic and hematopoietic diseases ; Humans ; Leukemia, Lymphoid - drug therapy ; Leukemia, Lymphoid - genetics ; Leukemias. Malignant lymphomas. Malignant reticulosis. 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These cells completely disappeared following chemotherapy. The significance of the Ph chromosome in T and B leukemic cells is discussed.</description><subject>Biological and medical sciences</subject><subject>Chromosomes, Human, 21-22 and Y</subject><subject>Chromosomes, Human, 6-12 and X</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemia, Lymphoid - drug therapy</subject><subject>Leukemia, Lymphoid - genetics</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>T-Lymphocytes</subject><subject>Translocation, Genetic</subject><issn>0165-4608</issn><issn>1873-4456</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRtFb_gUIPInqI7mY_cxGk-AUFPdTzMtlM6Oqmidmk0H9vakuPHoY5zPO-DA8hF4zeMcrU_TAyEYqaGyNvM5pylcgDMmJG80QIqQ7JaI-ckNMYvyilOs3UMTnmRqdM8RERHwsfoMDQLDwkTR1951c4mSfg-g4nYV01izoPEDvvJgH7b6w8nJGjEkLE890ek8_np_n0NZm9v7xNH2eJ40Z1CcsoFVIYzgUDoBokTwtIRclE6nheFgxZDppnTvBccMkzUDylRZFrxXVZ8jG53vY2bf3TY-xs5aPDEGCJdR-tVlRSY9gAii3o2jrGFkvbtL6Cdm0ZtRtZdmPCbkxYI-2fLCuH2OWuv88rLPahnZ3hfrW7Q3QQyhaWzsc9lrF0wPSAPWwxHFysPLY2Oo9Lh4Vv0XW2qP3_f_wCHW6EAA</recordid><startdate>19850415</startdate><enddate>19850415</enddate><creator>Louwagie, Andries</creator><creator>Criel, Arnold</creator><creator>Verfaillie, C.M.</creator><creator>Valcke, Y.J.</creator><creator>Lamberts, H.</creator><creator>Hidajat, M.</creator><creator>Mecucci, Cristina</creator><creator>Van Den Berghe, Herman</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19850415</creationdate><title>Philadelphia-positive T-acute lymphoblastic leukemia</title><author>Louwagie, Andries ; Criel, Arnold ; Verfaillie, C.M. ; Valcke, Y.J. ; Lamberts, H. ; Hidajat, M. ; Mecucci, Cristina ; Van Den Berghe, Herman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-190045483341aa07a532da24f142c3bfd1e1ba739c43b43539a6320ddb7637ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Biological and medical sciences</topic><topic>Chromosomes, Human, 21-22 and Y</topic><topic>Chromosomes, Human, 6-12 and X</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Leukemia, Lymphoid - drug therapy</topic><topic>Leukemia, Lymphoid - genetics</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>T-Lymphocytes</topic><topic>Translocation, Genetic</topic><toplevel>online_resources</toplevel><creatorcontrib>Louwagie, Andries</creatorcontrib><creatorcontrib>Criel, Arnold</creatorcontrib><creatorcontrib>Verfaillie, C.M.</creatorcontrib><creatorcontrib>Valcke, Y.J.</creatorcontrib><creatorcontrib>Lamberts, H.</creatorcontrib><creatorcontrib>Hidajat, M.</creatorcontrib><creatorcontrib>Mecucci, Cristina</creatorcontrib><creatorcontrib>Van Den Berghe, Herman</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer genetics and cytogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Louwagie, Andries</au><au>Criel, Arnold</au><au>Verfaillie, C.M.</au><au>Valcke, Y.J.</au><au>Lamberts, H.</au><au>Hidajat, M.</au><au>Mecucci, Cristina</au><au>Van Den Berghe, Herman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Philadelphia-positive T-acute lymphoblastic leukemia</atitle><jtitle>Cancer genetics and cytogenetics</jtitle><addtitle>Cancer Genet Cytogenet</addtitle><date>1985-04-15</date><risdate>1985</risdate><volume>16</volume><issue>4</issue><spage>297</spage><epage>300</epage><pages>297-300</pages><issn>0165-4608</issn><eissn>1873-4456</eissn><coden>CGCYDF</coden><abstract>A case of typical T-acute lymphoblastic leukemia (T-ALL) is reported in which, at diagnosis, 100% of bone marrow metaphases showed a Philadelphia (Ph) translocation, t(9;22). 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| ispartof | Cancer genetics and cytogenetics, 1985-04, Vol.16 (4), p.297-300 |
| issn | 0165-4608 1873-4456 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Chromosomes, Human, 21-22 and Y Chromosomes, Human, 6-12 and X Hematologic and hematopoietic diseases Humans Leukemia, Lymphoid - drug therapy Leukemia, Lymphoid - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged T-Lymphocytes Translocation, Genetic |
| title | Philadelphia-positive T-acute lymphoblastic leukemia |
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