Translocation t(1;5) in a case of carcinoma of the cervix

We report a case of carcinoma of the cervix uteri, which presented both numerical and structural chromosome changes. The tumor showed the coexistence of lines with different modal chromosome numbers, but all of them with the t(1;5)(q25;132). We also observed the presence of double minutes, dicentric...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1985-04, Vol.16 (3), p.269-273
Hauptverfasser:	Barbich, Mariana, Slavutsky, Irma, Larripa, Irene, Pasqualini, R.S., Brieux de Salum, Sonia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Chromosomes, Human, 1-3 Chromosomes, Human, 4-5 Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Medical sciences Translocation, Genetic Tumors Uterine Cervical Neoplasms - genetics
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Zusammenfassung:	We report a case of carcinoma of the cervix uteri, which presented both numerical and structural chromosome changes. The tumor showed the coexistence of lines with different modal chromosome numbers, but all of them with the t(1;5)(q25;132). We also observed the presence of double minutes, dicentric chromosomes, small acentric fragments, and/or tri- and quadriradial figures in 11% of the cells.
ISSN:	0165-4608 1873-4456
DOI:	10.1016/0165-4608(85)90054-8