In situ freezing of the pancreas and portal vein in the pig

The pathophysiological results of a study of simultaneously freezing the pancreas and portal vein in the pig are presented. There was little reduction in portal venous flow despite the vein being frozen, and there were no cases of occlusion, rupture, or dilatation of the vein. Major histological cha...

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Veröffentlicht in:	Cryobiology 1985-04, Vol.22 (2), p.183-190
Hauptverfasser:	McIntosh, G.S., Hobbs, K.E.F., O'Reilly, A.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences blood vessels carcinoma carcinome cerdo congelacion congelation Cryosurgery Freezing histologia histologie histology Liver, biliary tract, pancreas, portal circulation, spleen Medical sciences pancreas Pancreas - surgery porcin Portal Vein Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Swine tejido anatomia temperatura temperature tissu tissues vaisseau sanguin vasos sanguineos
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Zusammenfassung:	The pathophysiological results of a study of simultaneously freezing the pancreas and portal vein in the pig are presented. There was little reduction in portal venous flow despite the vein being frozen, and there were no cases of occlusion, rupture, or dilatation of the vein. Major histological changes in the vein wall were noted however. The frozen pancreatic tissue was completely destroyed and replaced by granulation tissue. The possible use of this form of therapy to treat pancreatic cancer is discussed.
ISSN:	0011-2240 1090-2392
DOI:	10.1016/0011-2240(85)90173-7