Circadian variations in serum zinc (Zn) concentrations: correlation with blood ionized calcium, serum total calcium and phosphate in humans

Serum zinc (Zn) concentrations were determined in sequentially drawn blood samples from six healthy adult males. Each subject had blood sampling performed every 30 minutes for 24 hours. Mean Zn concentrations at each time point (n = 6, 48 time points) were plotted and fitted by a polynomial regressi...

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Veröffentlicht in:	The American journal of clinical nutrition 1985-04, Vol.41 (4), p.689-696
Hauptverfasser:	Markowitz, ME, Rosen, JF, Mizruchi, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences BIOLOGICAL RHYTHMS BLOOD blood mineral concentrations Calcium - blood Cations, Divalent CINC Circadian Rhythm circadian rhythms Diet FOSFORO Fundamental and applied biological sciences. Psychology Humans Male Metabolisms and neurohumoral controls Models, Biological Phosphates - blood PHOSPHORE PHOSPHORUS RITMOS BIOLOGICOS RYTHME BIOLOGIQUE SANG SANGRE Vertebrates: anatomy and physiology, studies on body, several organs or systems Water and mineral metabolism. Osmoregulation. Acidobasic balance ZINC Zinc - blood
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Zusammenfassung:	Serum zinc (Zn) concentrations were determined in sequentially drawn blood samples from six healthy adult males. Each subject had blood sampling performed every 30 minutes for 24 hours. Mean Zn concentrations at each time point (n = 6, 48 time points) were plotted and fitted by a polynomial regression of the data against time. A “U” shaped curve was derived; we found peak Zn levels at 9:30 AM, a midtrough at 8 PM and a peak-trough difference of 19 µg/dl. Correlation with a similarly derived 24-h ionized calcium pattern was strikingly high, r = .923, p
ISSN:	0002-9165 1938-3207
DOI:	10.1093/ajcn/41.4.689