syn‐Selective Rhodium(I)‐Catalyzed Allylations of Ketimines Proceeding through a Directed CH Activation/Allene Addition Sequence

syn‐Selective Rhodium(I)‐Catalyzed Allylations of Ketimines Proceeding through a Directed CH Activation/Allene Addition Sequence

On a Rh‐oll: Rhodium(I)‐catalyzed CH activations of ketimines and subsequent carborhodation of an allene led to an allyl metal species, which then allylated the imine directing group to give highly functionalized methylene dihydroindenyl amines (see scheme) with excellent regio‐ and diastereoselect...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie (International ed.) 2010-10, Vol.49 (44), p.8181-8184
Hauptverfasser: Tran, Duc N, Cramer, Nicolai
Format: Artikel
Sprache:eng
Schlagworte:
allenes
allylation
annulation
CH activation
rhodium
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:On a Rh‐oll: Rhodium(I)‐catalyzed CH activations of ketimines and subsequent carborhodation of an allene led to an allyl metal species, which then allylated the imine directing group to give highly functionalized methylene dihydroindenyl amines (see scheme) with excellent regio‐ and diastereoselectivity.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201004179