Chikungunya virus-associated death in Malaysia

Chikungunya virus-associated death in Malaysia

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes fever, rash, and arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications and deaths. Mala...

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Veröffentlicht in:Tropical biomedicine 2010-08, Vol.27 (2), p.343-347
Hauptverfasser: Sam, I C, Kamarulzaman, A, Ong, G S Y, Veriah, R S, Ponnampalavanar, S, Chan, Y F, AbuBakar, S
Format: Artikel
Sprache:eng
Schlagworte:
Alphavirus Infections - epidemiology
Chikungunya Fever
Chikungunya virus - genetics
Fatal Outcome
Humans
Male
Middle Aged
Phylogeny
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Zusammenfassung:Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes fever, rash, and arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications and deaths. Malaysia is experiencing a nationwide outbreak of CHIKV, with over 10 000 patients affected since April 2008. We report the first case of culture-confirmed CHIKV-associated death in Malaysia, in a patient with fever, rash, acute exacerbation of pre-existing heart failure, rhabdomyolysis, and multiple organ failure. CHIKV infections may cause atypical, severe or fatal presentations.
ISSN:0127-5720