Cisplatin, vinblastine, and bleomycin therapy of yolk sac (endodermal sinus) tumor of the ovary
Five patients with yolk sac (endodermal sinus) tumor of the ovary were treated with cisplatin, vinblastine, and bleomycin combination therapy (PVB). Four of five achieved a complete remission and remain free from disease 24 to 53 months from start of PVB therapy. One patient did not respond well to...
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Veröffentlicht in: | Gynecologic oncology 1985-02, Vol.20 (2), p.162-169 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Five patients with yolk sac (endodermal sinus) tumor of the ovary were treated with cisplatin, vinblastine, and bleomycin combination therapy (PVB). Four of five achieved a complete remission and remain free from disease 24 to 53 months from start of PVB therapy. One patient did not respond well to PVB and died 11 months after start of PVB therapy. One patient who was treated with PVB after unilateral salpingo-oophorectomy has delivered a normal term infant. Serum α-fetoprotein levels were monitored in all patients during and after therapy. Serum α-fetoprotein was correlated with clinical course. |
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ISSN: | 0090-8258 1095-6859 |
DOI: | 10.1016/0090-8258(85)90137-4 |