Deletions of the long arm of chromosome 10

Patients with a partial deletion of the long arm of chromosome 10 are rare. We report eight new cases involving various segments of 10q: one terminal deletion (10q26), four (8;10) translocations resulting in terminal deletions (10q26) and duplications (8q24:3), a de novo interstitial deletion (10q23...

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Veröffentlicht in:	American journal of medical genetics 1985-01, Vol.20 (1), p.181-196
Hauptverfasser:	Shapiro, Steven D., Hansen, Kathryn L., Pasztor, Linda M., DiLiberti, John H., Jorgenson, Ronald J., Young, Robert S., Moore, Charleen M., Opitz, John M., Reynolds, James F.
Format:	Artikel
Sprache:	eng
Schlagworte:	10 13 Abnormalities, Multiple - genetics Adult Biological and medical sciences Child, Preschool chromosome 10 Chromosome aberrations Chromosome Deletion Chromosomes, Human, 6-12 and X Dermatoglyphics dup(q24.3) Face - abnormalities Female Humans Infant Intellectual Disability - genetics interstitial deletion Male Medical genetics Medical sciences multiple congenital anomaly (MCA) syndrome ring Ring Chromosomes terminal deletion translocation translocation (10 13) translocation (8 10) Translocation, Genetic
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Beschreibung
Zusammenfassung:	Patients with a partial deletion of the long arm of chromosome 10 are rare. We report eight new cases involving various segments of 10q: one terminal deletion (10q26), four (8;10) translocations resulting in terminal deletions (10q26) and duplications (8q24:3), a de novo interstitial deletion (10q23), an interstitial deletion due to a (10;13) translocation (10q11.2 → 10q22.1), and a ring (10p15 → 10q26).
ISSN:	0148-7299 1096-8628
DOI:	10.1002/ajmg.1320200122