Signal Pathway Regulation of Interleukin-8-Induced Actin Polymerization in Neutrophils

Interleukin-8 (IL-8), a recently described peptide cytokine, is a neutrophil chemoattractant and activator that exerts effects similar to fMLP, yet their receptors and their roles in pathophysiology differ. The effect of IL-8 on the neutrophil cytoskeleton has not been well studied; therefore, we co...

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Veröffentlicht in:Blood 1993-10, Vol.82 (8), p.2546-2551
Hauptverfasser: Sham, Ronald L., Phatak, Pradyumna D., Ihne, Trenton P., Abboud, Camille N., Packman, Charles H.
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Sprache:eng
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