Phospholipid composition of guinea pig lung lavage

Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65+0.67 mg, per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipids factions, i...

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Veröffentlicht in:	Lipids 1985-01, Vol.20 (1), p.7-10
Hauptverfasser:	Khan, Arshad Q., Sikpi, Matthew O., Das, Salil K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Fatty Acids - analysis Fundamental and applied biological sciences. Psychology Guinea Pigs Lipids Lung - analysis Male Other biological molecules Phosphatidylcholines - analysis Phospholipids - analysis Pulmonary Surfactants - analysis Therapeutic Irrigation
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Zusammenfassung:	Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65+0.67 mg, per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipids factions, in order of pedominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl‐choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained ostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76±0.42 mg.
ISSN:	0024-4201 1558-9307
DOI:	10.1007/BF02534355